Default PDA instrument method settings are frequently used for routine HPLC analysis. While these default settings are often suitable, they may need to be modified to obtain optimal separations. In ...

In the world of analytical chemistry, liquid chromatography (LC) has become indispensable in the analyst’s toolbox. Decades of research and refinement have brought many advances, in particular the ...

Method development in the modern HPLC laboratory is challenging but can be approached very logically and is hugely rewarding when a fit for purpose method is produced. This course provides you with ...

Investigation of peak purity failure during HPLC method validation led to discovery of a co-eluting impurity under the main peak. Spectral analysis, including three-dimensional modelling, was used to ...